Yalamanchili Lab

Bioinformatics Analyst I/Programmer I

About this Position:

A bioinformatics analyst or programmer position is immediately available in the laboratory of Dr. Hari Yalamanchili at the Neurological Research Institute (NRI), Baylor College of Medicine. Primary responsibilities include developing and application of various bioinformatics pipelines to high-throughput multi-omic datasets. Opportunities to expand knowledge in related areas of interest.

Responsibilities:

1. Evaluate, process and analyze high throughput Next Generation Sequencing datasets viz. RNA, ChIP, WGBS, Single-cell, etc.
2. Setup and maintain computational platform and analysis pipelines.
3. Meet with collaborators to present the analytical methods employed and reports generated.
4. Work closely with other computational and bench scientists.
5. Assist with drafting and completing manuscripts for publication.

Minimum Qualifications:

1. BS in Bioinformatics, Computer Science, Statistics or related field. MS is a plus.
2. Minimum one year experience in programming with R, Python, Perl or equivalents. C/C++ and JAVA are plus.
3. Working in UNIX environment. HPC/AWS is a plus.
4. Strong written, verbal and scientific communication skills.

Preferred Skills and attributes:

1. Working knowledge of genomics and familiarity with Next-Generation Sequencing technology tools and data analysis.
2. Understanding of statistics and machine learning.
3. Strong problem solving and trouble shooting skills.
4. Ability to handle multiple ongoing projects.
5. Creative and passion driven.

How to Apply:

Please email a cover letter and CV to hari.yalamanchili@bcm.edu

Postdoctoral Associate – Computational Biology

About this Position:

One bioinformatics postdoctoral scholar position is available immediately in the laboratory of Dr. Hari Yalamanchili at the Neurological Research Institute (NRI), Baylor College of Medicine. We seek a passion driven scientist with strong quantitative background and expertise in developing and applying computational models to study the fundamental and translational aspects of human diseases. This position is available as part of a research project with specific goals of developing novel computational methods to integrate large-scale high-throughput genomic, transcriptomic and proteomic data sets. The candidate will have the opportunity to interact with other computational and bench investigators and build a diverse range of expertise.

Minimum Qualifications:

1. PhD in Bioinformatics, Computer Science, Statistics or a related field.
2. Experience with bioinformatics algorithms, analytical pipelines and large-scale data analysis.
3. Demonstrated a good publication record in scholarly journals.
4. Proficiency in a language such as R, Python, Pearl. Java, C/C++ is a plus.
5. Good understanding of statistics, machine learning. Deep learning experience is a plus.
6. Working in UNIX environment. Experience in HPC and AWS to parallelize the execution of computational methods is a plus.

Desired Attributes:

1. Scientific creativity and passion.
2. Effective collaborative nature.
3. Accepts ownership and motivated by tough challenges

About the lab:

Laboratory of Dr. Hari Yalamanchili focuses on: Design and development of various computational approaches to decode complex biological phenomena and underlying molecular interplay. Specifically, to decode cryptic splicing, alternative polyadenylation and gene regulatory networks in neurological disorders. Advancing RNA centric therapeutic approaches using data driven integrative machine learning techniques.

About the Institution:

The Jan and Dan Duncan Neurological Research Institute (NRI) foster a multidisciplinary, collaborative environment to understand the genetic causes of various pediatric and adult neurological diseases and translate to novel therapeutic strategies. Website: http://www.nri.texaschildrens.org/

How to Apply:

Please email a cover letter and CV to hari.yalamanchili@bcm.edu